Maria Dube is a 37-year-old
Burlington woman with two young sons who has a
problem that's often hushed up, though it's shared
by 20 million Americans, two-thirds of them women.
The wear and tear of childbirth left Dube, a
telephone service representative for a Boston bank,
with stress incontinence, which meant that every
time she sneezed, laughed, jumped or chased her
kids, she leaked urine. Asthma made things even
worse. "I coughed so frequently, I had to use a pad
all the time," she said.
But several months ago, Dube underwent a
30-minute, minimally invasive surgical procedure
that, some doctors say, is the most dramatic
improvement in incontinence treatment in years.
While Dube was awake but under local anesthesia,
her physician, Dr. George Flesh, head of
urogynecology and pelvic reconstructive surgery at
Harvard Vanguard Medical Associates, implanted a
ribbon called a Tension-free Vaginal Tape between
her urethra, through which urine flows, and her
vagina. The tape is designed to act like a sling to
support the urethra. The procedure is so new that
only 20,000 patients worldwide have had it. Many
doctors, even in a medical mecca like Boston,
haven't yet had the special training to perform it.
But a three-year study in Sweden, where the
procedure was developed, shows it works 90 percent
of the time, and it clearly did for Dube.
Urinary incontinence comes in two basic forms:
urge problems, in which bladder muscles go into
spasm, making it impossible to stop urine flow once
it starts; and stress problems like Dube's, in which
weak sphincter or pelvic muscles fail to keep the
bladder neck closed during sudden physical stresses
like coughing or exercising.
Incontinence can also occur in men when an
obstruction - such as an enlarged prostate - blocks
urine flow, leading to overflow or urge problems.
While the vaginal tape procedure is creating the
biggest buzz, other new approaches - including an
acupuncture-like system called SANS and a
muscle-stimulating device called NeoControl - also
may dramatically improve the quality of life for
millions of incontinence patients.
For those with mild incontinence, the best way to
start is with the simplest, least-invasive options.
For stress incontinence, this means doing Kegel
exercises to strengthen pelvic floor muscles (the
muscles that support pelvic organs). To identify
these muscles, try stopping urine flow in midstream.
If you can, you've found the right muscles. Once
you've located them, practice this maneuver 100
times a day, but not during voiding, lest you retain
urine.
If you can't pinpoint the right muscles on your
own - and many people can't - go to a continence
center (many hospitals have them) and ask for
biofeedback training. Biofeedback is a system in
which electrical sensors are placed on patches of
skin or in the vagina or rectum; they send a
painless signal to let you know you're contracting
the right muscles.
A new alternative, NeoControl, may be more
appealing for some people with stress or urge
incontinence. You sit on a special chair, fully
clothed, with an empty bladder. Magnets under the
chair produce a pulsed magnetic field that acts on
nerves to cause pelvic muscles to contract.
"When you stand up, you feel like you just got
out of the gym, but only in the pelvis. It feels
sore but not unpleasant, like a workout," said Dr.
Peter Rosenblatt, a urogynecologist and codirector,
with Dr. Neeraj Kohli, of the Cambridge Continence
Center at Mt. Auburn Hospital in Cambridge.
About 60 percent of patients who use NeoControl
improve after two months of twice-weekly sessions,
Rosenblatt said.
Vaginal cones, which are available by
prescription, are another simple solution for stress
and urge problems. These are tampon-like devices
held in the vagina for 15 minutes twice a day to
strengthen muscles.
Other devices, also available by prescription,
include Capsure and FemAssist, which are reusable
suction cups that cover the opening of the urethra
and are pulled off before urination. There is also a
disposable patch called Impress that sticks to the
urethral opening like a BandAid; it, too, must be
changed before urination, but it may be available
over-the-counter soon.
If urge incontinence is your problem, bladder
retraining may help. The idea is to stick to a
pre-set schedule, urinating regularly before the
bladder gets too full, and learning to suppress the
urge to urinate at other times. A variant on this is
the AcuTrainer, a prescription beeper that your
doctor programs to tell you when to urinate. The
program gradually increases the interval between
voids.
Recently, the US Food and Drug Administration
approved another option for urge incontinence, the
SANS (for Stoller Afferent Nerve Stimulation)
system, after research showed that 55 percent of
women who tried it had at least a 25 percent
reduction in urgency or frequency.
In SANS, the tip of an acupuncture-type needle is
placed just under the skin above the ankle, a site
known to acupuncturists as "spleen 6." A mild
electrical current is passed through the needle to
stimulate a nerve that controls the sacral nerve in
the lower back, which in turn controls the bladder.
The treatment calms the nerves to the bladder, which
are hypersensitive in many people with urge
incontinence.
The SANS treatment is similar to a more invasive,
and expensive, surgical procedure in which a device
called InterStim is implanted in the lower back to
control nerves to the bladder.
And there are other options, too. For stress
incontinence, especially a severe form called
intrinsic sphincter deficiency, collagen injections
- via a needle passed through the urethra - fill the
space around the urethra, squeezing off urine flow.
A similar approach involves injections with
Durasphere - carbon pellets in a gel-like
suspension. Unlike collagen injections, whose effect
tends to wear off after two years, Durasphere
injections should last longer because the material
is not absorbed by the body.
For sheer convenience, however, many people opt
for medications rather than devices.
Estrogen can make the urethra more pliable and
help it close more easily. It can be taken as pills,
patches, vaginal cream or a vaginal ring called
Estring that releases the hormone slowly over three
months.
Nasal decongestants like Sudafed and a
prescription decongestant called Entex can also help
with stress incontinence because, as a side effect,
these drugs act on proteins called alpha-receptors,
which help the urethra contract.
For urge incontinence, other drugs help - notably
the old standbys Ditropan and Levbid, and newer ones
such as Detrol and Ditropan XL (extended release).
These drugs block acetylcholine, a chemical secreted
by nerves that tells muscles to contract. The newer
drugs cause fewer side effects like dry mouth and
constipation.
Tofranil, an antidepressant that, like the
decongestants, has the useful side effect of
relaxing bladder spasms and tightening the urethra,
can also help. For men with incontinence caused by
an enlarged prostate, drugs like Hytrin or Flomax
that relax the urethra also work. So does shrinking
the prostate itself - with drugs or surgery.
Surgery is an option for some women, too. For
those with stress incontinence, the traditional
approach is the Burch procedure, a "suspension"
technique in which surgeons tighten up the pelvic
fascia (fibrous tissue that lies on top of muscles)
by stitching it to ligaments near the pubic bone.
Traditionally, this is done through an open
abdominal incision, which means the patient spends
several days in the hospital, but can count on an 80
to 90 percent chance of being markedly improved for
at least five years.
Recently, some surgeons - perhaps half a dozen in
Boston - have been using a laparoscopic approach.
Instead of making a 4- to 5inch abdominal incision,
they operate through two tiny incisions using
miniature TV cameras to guide their way. The surgery
is technically difficult, but appears to have the
same success rate as the standard Burch procedure.
But it's the new vaginal tape procedure that may
prove most appealing for women whose main problem is
a sagging urethra, not a sagging bladder as well.
"It's fantastic," said Rosenblatt of Mt. Auburn
Hospital, who has done 150 such procedures. So far,
it seems to enable women to have less pain, a
shorter recovery and to solve the problem in 85 to
90 percent of cases.
Dube, the energetic mother who had the tape
procedure, agreed. "I used to have to cross my legs
every time I sneezed," she said. "Now I swim, run,
everything. I don't have to use pads." Her advice?
"Just do it. It will take a week of your time" to
fully heal. "But it's worth it."