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Judy's Response |
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Topic: |
Preeclampsia |
Date: |
03/31/08 | |
| Questions: |
Does preeclampsia put women at higher risk of cardiac
problems later?
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| Response: |
Yes, there is definitely a correlation between preeclampsia -
high blood pressure and protein in the urine during pregnancy -
and cardiovascular problems in later life. But it's not clear
whether preeclampsia itself is the culprit or whether women who
get preeclampsia were already at risk of future cardiovascular
problems before they got pregnant, said Dr. Richard J. Levine,
an epidemiologist at the National Institute of Child Health and
Human Development at the National Institutes of Health.
Preeclampsia almost always occurs about halfway through a
normal, 40-week pregnancy. It's quite common, occurring in
roughly 5 percent of pregnancies, and accounts for about 15
percent of premature births as well as the death of several
hundred Americans per year, according to the Preeclampsia
Foundation.
Recent research shows that preeclampsia is caused by an
imbalance between two kinds of factors, those that turn on and
those that shut down new blood vessel growth, said Dr. Benjamin
Sachs, formerly the head of obstetrics at Beth Israel Deaconess
Medical Center and now dean of the Tulane University School of
Medicine.
At the beginning of pregnancy, a woman has to create more blood
vessels to increase the blood supply to a growing baby, a
process called angiogenesis. At the end of pregnancy, this
process needs to be reversed, otherwise a woman could bleed
heavily. In preeclampsia, the shutdown of blood vessel growth
occurs too early which can lead to damage to blood vessels, the
kidneys, liver, and brain, Sachs said.
The bottom line is that women who have had preeclampsia should
be extra careful throughout their lives to monitor blood
pressure and cholesterol, control weight, and take blood
pressure-lowering medication if necessary.
It's not clear yet whether the babies of women who have
preeclampsia are also at increased risk of cardiovascular
problems later in life.
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